Publications

Woldring DR, Holec PV, Stern LA, Du Y & Hackel BJ. A gradient of sitewise diversity promotes evolutionary fitness for binder discovery in a three-helix bundle protein scaffold. Biochemistry 2017

Stern LA, Csizmar CM, Woldring DR, Wagner CR, Hackel BJ. Titratable avidity reduction enhances affinity discrimination in mammalian cellular selections of yeast-displayed ligands. ACS combinatorial science 2017

Hackel BJ, Woldring DR, Zhou H. Compositions and methods that involve protein scaffolds that specifically bind to hepatocyte growth factor receptor. US Patent App. 16/158,957

Woldring DR, Holec PV & Hackel BJ. ScaffoldSeq: Software for Characterization of Directed Evolution Populations. Proteins: Structure, Function and Bioinformatics 2016

Kruziki MA, Case BA, Chan JY, Zudock EJ, Woldring DR, Yee D & Hackel BJ. 64Cu-Labeled Gp2 Domain for PET Imaging of Epidermal Growth Factor Receptor. Molecular Pharma. 2016

Woldring DR, Holec PV, Zhou H & Hackel BJ. High-Throughput Ligand Discovery Reveals a Sitewise Gradient of Diversity in Broadly Evolved Hydrophilic Fibronectin Domains. PLoS One 2016

Kruziki MA, Bhatnagar S, Woldring DR, Duong VT, Hackel BJ. A 45-amino-acid scaffold mined from the PDB for high-affinity ligand engineering. Chemistry & biology. 2015

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